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By Duane J. Gubler, Eng Eong Ooi, Subhash Vasudevan, Jeremy Farrar

Greater than 20,000 deaths are linked to dengue virus infections every year, and DF/DHF is without doubt one of the most vital rising tropical illnesses on the planet. contemporary intriguing examine on dengue viruses has led to significant advances in our figuring out of all facets of the biology of dengue viruses. This up to date moment variation brings jointly best study and scientific scientists to check the most recent findings on dengue virus biology, epidemiology, entomology, therapeutics, vaccinology and medical administration.

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1789) An account of the bilious remitting fever, as it appeared in Philadelphia in the summer and autumn of the year 1780. Medical Inquiries and Observations. Prichard & Hall, Philadelphia, Pennsylvania, pp. 104–117. B. (1952) Research on dengue during World War II. American Journal of Tropical Medicine and Hygiene 1, 30–50. B. C. (1945) Production of immunity to dengue with virus modified by propagation in mice. Science 101, 640–642. J. C. L. (1985) Dengue in northeast Africa. The Lancet 326, 211–212.

Prior to 1981 Africa Surveillance for dengue in Africa was exceptionally poor during the 20th century, with the disease rarely being reported. Prior to the 1980s, the last recorded epidemic was in Durban, South Africa, in 1927/28. , 1971), but major outbreaks were not reported. However, reports of epidemic dengue fever have increased dramatically since 1980. , 1994). The 2009 epidemic of DENV-3 in the Cape Verde Islands, with over 17,000 cases, was the first reported in those islands. , 2011). While surveillance for reported cases is still poor in the countries themselves, the global GeoSentinel surveillance system and recent increased travel has 1981–2012 Fig.

1907) Experimental investigations regarding the etiology of dengue fever. Journal of Infectious Disease 4, 440–475. L. (1906) On the aetiology of dengue fever. Australian Medical Gazette 25, 17–18. S. and Rosen, L. (1974) Fatal hemorrhagic disease and shock associated with primary dengue infection on a Pacific island. American Journal of Tropical Medicine and Hygiene 23, 495–506. J. (1928) The distribution of Stegomyia fasciata in India, with remarks on dengue and yellow fever. Indian Journal of Medical Research 16, 377–388.

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