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By David Isaacs

Evidence-Based Neonatal Infections is expertly written via David Isaacs, an skilled writer popular for his wisdom in either pediatric infections and evidence-based medication. It severely analyses the proof for choice making in neonatal infections.

Evidence-Based Neonatal Infections

* The first evidence-based textual content on neonatal infections

* Provides sensible information the place facts is poor

* Complements David Isaacs’ Evidence-Based Pediatric Infectious Diseases (9781405148580)

Practical and evidence-based, Evidence-Based Neonatal Infections is designed to aid the clinician with daily judgements at the care of baby infants with attainable, possible or confirmed infections. It considers medical questions appropriate to neonatologists, analysing the facts conscientiously and offering options for max administration of neonatal infectious ailments, while reflecting on:

  • Efficacy and safety
  • Antibiotic resistance
  • Cost effectiveness
  • Adverse effects
  • Ethical considerations

Evidence-Based Neonatal Infections offers a different reference for neonatologists, pediatricians, trainees, expert nurses; common practitioners, microbiologists, an infection regulate medical professionals, and all employees in neonatal units.

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Sample text

Christensen RD, Henry E, Wiedmeier SE, Stoddard RA, Lambert DK. Low blood neutrophil concentrations among extremely low birth weight neonates: data from a multihospital health-care system. J Perinatol 2006; 26:682– 687. Sarkar S, Bhagat I, Hieber S, Donn SM. Can neutrophil responses in very low birth weight infants predict the organisms responsible for late-onset bacterial or fungal sepsis? J Perinatol 2006; 26:501–505. Manzoni P, Mostert M, Galletto P, et al. Is thrombocytopenia suggestive of organism-specific response in neonatal sepsis?

Faix RG, Kovarik SM. Polymicrobial sepsis among intensive care nursery infants. J Perinatol 1989; 9:131–136. 18. Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. Matched case-control analysis of polymicrobial bloodstream infection in a neonatal intensive care unit. Infect Control Hosp Epidemiol 2008; 29:914–920. 19. Visser VE, Hall RT. Lumbar puncture in the evaluation of suspected neonatal sepsis. J Pediatr 1980; 96:1063– 1067. 20. Fielkow S, Reuter S. Gotoff SP. Cerebrospinal fluid examination in symptom free infants with risk factor for infection.

51 Thus thrombocytopenia can occur with CoNS, Gramnegative and fungal infection and the relative likelihood depends on local epidemiology and on individual infant factors such as gestational age and prior antibiotic use. Recommendation: Late, severe thrombocytopenia is a strong indication to start antimicrobials but both Gram-negative and Gram-positive covers are essential, while empiric antifungals should be considered in high-risk infants. 1 Serum C-reactive protein C-reactive protein (CRP) is a protein produced by the liver in response to infectious and non-infectious inflammatory processes.

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