Download Handbook of Genetics: Volume 5: Molecular Genetics by Neil A. Straus (auth.), Robert C. King (eds.) PDF

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By Neil A. Straus (auth.), Robert C. King (eds.)

Many glossy geneticists try to elucidate the molecular foundation of phenotype by using a battery of innovations derived from actual chemistry on subcellular parts remoted from quite a few species of organisms. quantity five of the instruction manual of Genetics presents factors of the benefits and shortcomings of a few of those innovative tech­ niques, and the nonspecialist is alerted to key study papers, experiences, and reference works. a lot of the textual content bargains with the constitution and func­ tioning of the molecules bearing genetic info which dwell within the nucleus and with the processing of this data via the ribosomes resid­ ing within the cytoplasm of eukaryotic cells. The mitochondria, which additionally dwell within the cytoplasm of the cells of all eukaryotes, now seem to be separate little creatures. those, as Lynn Margulis mentioned in quantity 1, are the colonial posterity of migrant prokaryotes, most likely primitive micro organism that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. they've got maintained themselves and their methods ever on the grounds that, replicating their very own DNA and transcribing an RNA fairly various from that in their hosts. In an analogous demeanour, the chloroplasts in all vegetation are self-replicating organelles possibly derived from the blue-green algae, with their very own nucleic acids and ribosomes. 4 chapters are dedicated to the nucleic acids and the ribosomal parts of either periods of those semi-independent lodgers. ultimately, information from quite a few resources on genetic editions of enzymes are tabulated for prepared reference, and an overview of this knowledge is attempted.

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Paul, 1974 In situ localization of globin messenger RNA formation. I. During mouse fetal liver development. J. Cell Bioi. 63:402-413. Hearst, J. , T. R. Cech, K. A. Marx, A. Rosenfeld, and J. R. Allen, 1974 Characterization of the rapidly renaturing sequences in the main CsCI density bands of Drosophila, mouse, and human DNA. Cold Spring Harbor Symp. Quant. Bioi. 38: 329-339. ;ys 50 Q. The Molecular Organization of Chromosomes Henderson, A. , D. Warburton, and K. C. Atwood, 1972 Location of ribosomal DNA in the human chromosome complement.

66:339-361. Flamm, W. , 1972 Highly repetitive sequences of DNA in chromosomes. Int. Rev. Cytol. 32: 1-51. , B. Bierweiler, and H. W. Sauer, 1974 Reassociation kinetics of nuclear DNA from Physarum polycephalum. Eur. J. Biochem. 44:407-410. Gage, L. , 1974 The Bombyx mori genome: Analysis by DNA reassociation kinetics. Chromosoma 45:27-42. Gall, J. G. 1969 Genes for ribosomal RNA during oogenesis, Genetics Suppl. 1, Part 261:121-132. Gall, J. , E. H. Cohen, and M. L. Polan, 1971 Repetitive DNA sequences in Drosophila.

T. C. Hsu, S. Pathak, and H. Sawada, 1974 The sex chromosomes of the Chinese hamster: Constitutive heterochromatin deficient in repetitive DNA sequences. Cytogenet. Cell Genet. 13:268-274. , M. Buongiorno-Nardelli, P. G. Cionini, and F. D'Amato, 1971 Cytological localization of molecular hybrids between rRNA and DNA in the embryo suspensor cells of Phaseolus coccineus. Accad. Naz. Lincei Rendic. C. Sci. Fis. Mat. Nat. Ser. VIII 50:357-361. , M. Durante, P. G. Cionini, and F. D'Amato, 1972 Cytological localization of ribosomal cistrons in polytene chromosomes of Phaseolus coccineus.

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