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By Jawetz

Linking primary microbiology options with the prognosis and remedy of medical infections, this distinctive, moveable textual content offers a necessary evaluate of the organisms and brokers serious about medical microbiology. as well as short descriptions of the organisms, you can find very important views on pathogenesis, diagnostic laboratory checks, medical findings, remedy, and epidemiology. The book's goal is to introduce uncomplicated scientific microbiology throughout the fields of bacteriology, virology, mycology, and parasitology supplying you with a far-reaching, but obtainable evaluation of the self-discipline that you just cannot locate at any place else. assisting this acclaimed assurance are greater than three hundred informative illustrations and tables, every one designed to elucidate and force domestic very important bankruptcy suggestions.

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Sample text

30,32,33 The process of gliding motility requires the coordinated activities of protein secretion and translocation via the actin-based cytoskeleton. Adhesion to the cell substrate and host cell receptors is largely mediated by microneme proteins,34 which are discharged apically from small secretory vesicles. 15 Apically discharged adhesins form contacts with the substrate or host cell surface. These adhesin complexes are translocated rearward by the underlying actin-myosin cytoskeleton, thus propelling the parasite forward.

Barragan A, Sibley LD. Transepithelial migration of Toxoplasma gondii is linked to parasite motility and virulence. J Exp Med 2002; 195:1625-1633. 17. Barragan A, Sibley LD. Migration of Toxoplasma gondii across biological barriers. Trends Microbiol 2003; 11:426-430. 18. Arrowood MJ, Sterling CR, Healey MC. Immunofluorescent microscopical visualization of trails left by gliding Cryptosporidium parvum sporozoites. J Parasitol 1991; 77:315-317. 19. King CA. Cell surface interaction of the protozoan Gregarina with Concanavalin A beads - Implications for models of gregarine gliding.

King CA. Cell motility of sporozoan protozoa. Parasitol Today 1988; 11:315-318. 14. Sibley LD. Invasion strategies of intracellular parasites. Science 2004; 304:248-253. 15. Håkansson S, Morisaki H, Heuser JE et al. Time-lapse video microscopy of gliding motility in Toxoplasma gondii reveals a novel, biphasic mechanism of cell locomotion. Mol Biol Cell 1999; 10:3539-3547. 16. Barragan A, Sibley LD. Transepithelial migration of Toxoplasma gondii is linked to parasite motility and virulence. J Exp Med 2002; 195:1625-1633.

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