By Richard P. Feynman
A portrait of the overdue Nobel Prize-winning physicist according to his personal phrases and people of his buddies, kin, and co-workers recounts his early enthusiasm for technological know-how, paintings at the atom bomb and the inquiry into the Challenger catastrophe, and different reports. 15,000 first printing
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Additional info for No ordinary genius : the illustrated Richard Feynman
10 shows the two enantiomers of amphetamine. 10 The tivo enantiomers of’ amphetamine Whereas enantiomeric pairs are common, there are far fewer instances of controlled drugs with two or more chiral centres. A good example of diastereoisomerism occurs in 1-hydroxy- 1-phenyl-2-aminopropane. 1 l(4). The lS,2S isomer, ( + )norpseudoephedrine, is also known as cathine (Class C). e. ( + ) and (-)norephedrine respectively, when present as a racemic mixture, are known as phenylpropanolamine: a decongestant drug.
An exception to this is found in geometrical stereoisomers which have no chiral centre. Steric hindrance can produce a rotameric pair, an example of which is found in the non-controlled drug gossypol). Different spatial arrangements at one chiral centre give rise to two molecules that are related as mirror images, and are called enantiomers. Such molecules are normally optically active (they rotate the plane of polarised light) and were formerly designated (D) or (+) or as (L) or (-). e. a mixture of equal These terms numbers of (+) and (-) molecules, shown as (DL) or (2).
13), which would otherwise be included in the generic definition, is specifically excluded since it has clinical value as an adrenocortical suppressant used in the treatment of breast cancer. 1 BRITISH APPROVED NAMES AND INTERNATIONAL NON-PROPRIETARY NAMES In common with most chemical substances, a given drug may have a number of synonyms. Wherever possible, the Act uses the British Approved Name (BAN), which is defined by the British Pharmacopoeia Commission. In general, a BAN only exists for drugs that have or have had clinical value.