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By Peter Hegemann

Optogenetics combines genetic engineering with optics to monitor and keep an eye on the functionality of cells utilizing gentle, with medical implications for recovery of imaginative and prescient and therapy of neurological illnesses. As a brand new self-discipline a lot of the elemental technological know-how and strategies are at present less than research and energetic improvement, therefore there's a powerful want for introductory literature during this box. This graduate point textbook presents an outline of the sector of optogenetics in five concise chapters: Optogenetic instruments, purposes in mobile platforms, Mapping neuronal networks, medical purposes and recovery of imaginative and prescient and listening to. the idea that and content material was once constructed with best overseas researchers and scholars at a prestigious Dahlem convention workshop.

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J. Mol. Biol. 2002; 321: 715–26. [14] Yang X, Kuk J, Moffat K. Crystal structure of Pseudomonas aeruginosa bacteriophytochrome: Photoconversion and signal transduction. Proc. Natl. Acad. Sci. USA 2008; 105: 14715–20. [15] Ryu M-H, Moskvin OV, Siltberg-Liberles J, Gomelsky M. Natural and engineered photoactivated nucleotidyl cyclases for optogenetic applications. J. Biol. Chem. 2010; 285: 41501–8. [16] Stierl M, Stumpf P, Udwari D, Gueta R, Hagedorn R, Losi A, Gärtner W, Petereit L, Efetova M, Schwarzel M, Oertner TG, Nagel G, Hegemann P.

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