By C.S. Potten (Eds.)
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Additional resources for Stem Cells
If it is true that the differentiated state requires continuous regulation for its maintenance (Blau and Baltimore, 1991; Blau, 1992), then each domain in the root actively maintains either its own state or that of a neighbouring domain, or both.
The latter occur when new axes are developed from nodes. In the five schemes (i-v) there may be up to five different states, A-E. ) A new axis (or axes) (m) develops at each developmental step. At the cellular level, the emergence of two axes from each node represents the division of a cell into two daughters; this may (in iv and v) or may not (in i, ii or iii) be accompanied by a change in state. Whether or not a change in state occurs depends upon a probability, P, or upon a counter, ;~, of time or some event such as cell divisions.
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