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By Institute of Medicine, Board on Population Health and Public Health Practice, Committee on the Assessment of Studies of Health Outcomes Related to the Recommended Childhood Immunization Schedule

"The youth Immunization time table and security: Stakeholder matters, medical facts, and destiny reports experiences medical findings and stakeholders issues on the topic of the protection of the instructed formative years immunization agenda. This record additionally identifies capability learn ways, methodologies and examine designs which can tell this question, contemplating strengths, weaknesses in addition to moral and  Read more...

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Extra resources for The childhood immunization schedule and safety : stakeholder concerns, scientific evidence, and future studies

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Randomized controlled trials with important limitations or exceptionally strong evidence from observational studies; 3. observational studies or randomized controlled trials with notable limitations; and 34 THE CHILDHOOD IMMUNIZATION SCHEDULE AND SAFETY 4. clinical experience and observations, observational studies with important limitations, or randomized controlled trials with several major limitations. Recommendations from ACIP are also categorized into Category A or B recommendations, although the distinction does not reflect the quality of the evidence reviewed.

PAST AND PRESENT IMMUNIZATION SCHEDULES The current schedule of recommended immunizations for infants and children from birth through age 6 years comprises vaccines that prevent 14 infectious diseases, a remarkable achievement compared with the schedule in 1948, when immunizations against only diphtheria, tetanus, pertussis, and smallpox were available and recommended for administration for protection. In 1955, the polio vaccine was licensed and added to the recommended immunizations to eliminate yearly outbreaks.

This chapter reviews these systems and discusses how data from these systems are used to help assess the safety of cumulative immunizations, the timing of immunizations, and other aspects of the immunization schedule. IMMUNIZATION SAFETY SURVEILLANCE A number of systems for ongoing monitoring and study of the safety of vaccines recommended for use are in place in the United States (and other nations as well), where the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), and vaccine manufacturers have systems in place for postmarketing surveillance and research.

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