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By T. Ryan Gregory

The Evolution of the Genome presents a miles wanted evaluation of genomic research via transparent, designated, expert-authored discussions of the foremost parts in genome biology. This contains the evolution of genome dimension, genomic parasites, gene and historic genome duplications, polypoidy, comparative genomics, and the results of those genome-level phenomena for evolutionary thought. as well as reviewing the present country of data of those fields in an available manner, some of the chapters additionally supply ancient and conceptual heritage info, spotlight the ways that the severe questions are literally being studied, point out a few vital components for destiny learn, and construct bridges throughout conventional expert and taxonomic boundaries.The Evolution of the Genome will function a severe source for graduate scholars, postdoctoral fellows, and proven scientists alike who're attracted to the problem of genome evolution within the broadest feel. ·Provides specified, in actual fact written chapters authored through major researchers of their respective fields·Presents a much-needed assessment of the historic and theoretical context of some of the components of genomic study·Creates very important hyperlinks among themes as a way to advertise integration throughout subdisciplines, together with descriptions of ways every one topic is absolutely studied·Provides info in particular designed to be obtainable to verified researchers, postdoctoral fellows, and graduate scholars alike

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When referring to diploid species, “C-value” and “genome size” are interchangeable, but these terms must be used more judiciously when dealing with polypoids (see also Chapter 2). THE C-VALUE PARADOX Accepting that genome size constancy within species reflected the role of DNA as the hereditary substance, the obvious implication was that “this constant is probably proportionate to the number of genes” (Vendrely and Vendrely, 1950; translation by the present author). However, this hypothesis began to unravel almost immediately after large comparisons were made across species (Fig.

On January 10, 2001, the Animal Genome Size Database was launched online (Gregory, 2001b). At present, the Animal Genome Size Database contains almost as many data as the Plant DNA C-values Database—nearly 4000 species, including roughly 2500 vertebrates and 1300 invertebrates. 1 Summary of the basic patterns of genome size variation in the better-studied groups of animals. This includes ranges and means, as well as the number of species studied to date, with the percentage of described species covered given in brackets.

This was accomplished by computing the DNA concentration of bulk tissue preparations divided by nucleus numbers estimated from suspension counts. These studies revealed nuclei in each of these tissues to contain an approximately equal amount of DNA, that being roughly twice the value contained in sperm from the same species. Thus, Vendrely and Vendrely (1948) reported “a remarkable constancy in the nuclear DNA content of all the cells in all the individuals within a given animal species” (translation by the present author).

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