By Bruce L. Larson
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Extra info for The Mammary Gland/Human Lactation/Milk Synthesis
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The basal lamina (BL) is thickened in the hemidesmosome region, and several anchoring fibrils (arrowheads) extend from it out among abundant collagen fibrils, seen here in cross section, x50,000.
Both of the latter functions require directed activity, or polarity, on the part of the cells, and, of course, all cells in the epithelium must be polarized in the same direction. All three functions require that intercellular spaces in the sheet be somehow blocked, to restrict diffusion of substances by this route between the two compartments. Functional polarization is reflected in a surface polarity that is characteristic of most transporting epithelia (Farquhar and Palade, 1963; Berridge and Oschman, 1972).