By E. Carniel
Horizon clinical Press titles specialize in high-level microbiology and molecular biology issues. Written via across the world popular and hugely revered leaders within the box, they contain assessment manuals, sensible manuals, and reference texts for learn scientists, bioscience pros and graduate scholars. Yersinia traces are very important human pathogens inflicting illnesses starting from the lethal Plague ( Yersinia pestis ) to a comparatively light gastroenteritis (e.g. Y. enterocolitica and Y. pseudotuberculosis) . Plague is presently classed as a re-emerging illness that's endemic in lots of elements of the realm. on the grounds that Y. pestis is very deadly (a very small variety of bacilli are adequate to kill a person in a question of days) it can be utilized by bioterrorists as an impressive airborne adversary. This has supplied the impetus for a renewed curiosity in Yersinia molecular and mobile biology. Written by means of the head Yersinia experts, the booklet reports the molecular biology of those very important organisms and comprehensively covers contemporary advances within the box. themes comprise genetic range in Y. pestis, quorum sensing, identity of virulence genes, rules of virulence components, superantigens, host invasion, host immune reaction, LPS constitution and genetics, flagellar-dependent motility, flagellar-dependent protein secretion, iron or heme delivery structures, Yersinia pathogenicity Islands, the Yop effector proteins, plasminogen activator (Pla), F1 antigen, and the conjugative plasmid pVM82. crucial analyzing for everybody with an curiosity in Yersinia and instructed studying for different scientists with an curiosity in, for instance, bioterrorism, microbial pathogenesis, microbial genomics, and antimicrobials.
Read Online or Download Yersinia: Molecular and Cellular Biology PDF
Best molecular biology books
This ebook emphasises the unifying ideas and mechanisms of molecular biology, with common use of tables and packing containers to summarise experimental information and gene and protein capabilities.
This quantity is devoted to an outline of the tools, samples, protocols, and analyses that belong to cryo-EM. It emphasizes the relatedness of the tips, intrumentation, and strategies underlying all cryo-EM ways which enable practictioners to simply circulate among them. inside of every one part, the articles are ordered in line with the commonest symmetry of the pattern to which their tools are utilized.
To appreciate the buildings and dynamics of DNA and its interactions with ligands, an entire research of its confirmational flexibility is needed. This quantity and its spouse, quantity 212 of equipment in Enzymology, collate in a single resource all of the equipment and methods had to accomplish that target
The severely acclaimed laboratory typical for greater than 40 years, tools in Enzymology is likely one of the so much hugely revered courses within the box of biochemistry. considering the fact that 1955, every one quantity has been eagerly awaited, usually consulted, and praised by way of researchers and reviewers alike. Now with greater than three hundred volumes (all of them nonetheless in print), the sequence comprises a lot fabric nonetheless correct today--truly a vital book for researchers in all fields of lifestyles sciences
- Protein Purification: Principles and Practice
- Transcription Factors in the Nervous System: Development, Brain Function, and Diseases
- RNA and DNA Editing: Molecular Mechanisms and Their Integration into Biological Systems
Extra resources for Yersinia: Molecular and Cellular Biology
Recent emergence of new variants of Yersinia pestis in Madagascar. J. Clin. Microbiol. 35:2826–2833. E. 1994. Clonal divergence in Escherichia coli as a result of recombination, not mutation. Science 266:1380–1383. G. 1998. Evaluation of the role of Yersinia pestis plasminogen activator and other plasmid-encoded factors in temperature-dependent blockage of the flea. J. Infect. Dis. 178: 1406–1415. , and Carniel, E. 2002a. High-frequency conjugative transfer of antibiotic resistance genes to Yersinia pestis in the flea midgut.
Mol. Biol. Evol. 2:150–174. G. 1998. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc. Natl. Acad. Sci. USA. 95:3140–3145. , Sokhansanj, B. , and Garcia, E. 2002. Genetic variability of Yersinia pestis isolates as predicted by PCR-based IS100 genotyping and analysis of structural genes encoding glycerol-3-phosphate dehydrogenase (glpD). J. Bacteriol. 184:1019–1027. A. 1999. Calibrating bacterial evolution. Proc.
96:14043–14048. B. 2004. Intraspecific diversity of Yersinia pestis. Clin. Microbiol. Rev. in press. , and Brenner, D. J. 1980. Intra- and interspecies relatedness of Yersinia pestis by DNA hybridization and its relationship to Yersinia pseudotuberculosis. Curr. Microbiol. 4:225–229. , and Mollaret, H. 1994. Pourquoi la peste? Le rat, la puce et le bubon. Gallimard, Paris, France, p. 1–160. , and Glaser, P. 1999. The 102 kb pgm locus of Yersinia pestis: sequence analaysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains.